Welcome to Frank Lab

We investigate the mechanism of translation on the ribosome by using cryo-electron microscopy and single-particle reconstruction.
 


Recent Publications



Article: Whither Ribosome Structure and Dynamics Research?
(A Perspective)

Journal: Journal of Molecular Biology
Authors: Joachim Frank
[Abstract]

Article: Continuous Changes in Structure Mapped by Manifold Embedding
of Single-Particle Data in Cryo-EM

Journal: Methods
Authors: Joachim Frank, Abbas Ourmazd
[Abstract]

Article: Generalized single-particle cryo-EM – a historical perspective
Journal: Microscopy
Authors: Joachim Frank
[Abstract]

Article: Dynamical features of the Plasmodium falciparum ribosome
during translation

Journal: Nucleic Acids Research Journal
Authors: Ming Sun, et al.
[Abstract]

Article: Structure of mammalian eIF3 in the context of the 43S
preinitiation complex

Journal: Nature
Authors: Amedee Des Georges, et al.
[Abstract]

Article: Structural dynamics of ribosome subunit association studied by
mixing-spraying time-resolved cryo-EM

Journal: Structure
Authors: Bo Chen, et al.
[Abstract]

Article: Activation of GTP Hydrolysis in mRNA-tRNA Translocation by
Elongation Factor G

Journal: Science Advances
Authors: Wen Li, et al.
[Abstract]

Article: Efficient estimation of three-dimensional covariance and its application
in the analysis of heterogeneous samples in cryo-electron microscopy

Journal: Structure
Authors: Hstau Y. Liao, et al.
[Abstract]

Article: CTF Challenge: Result summary
Journal: Journal of Structural Biology
Authors: Roberto Marabini, et al.
[Abstract]

Article: Quantitative connection between ensemble thermodynamics and
single-molecule kinetics

Journal: The Journal of Physical Chemistry
Authors: Colin D. Kinz-Thompson, et al.
[Abstract]


Recent News


Jingji Zhang receives PhD
June 22, 2016

Congratulations to Jingji Zhang on receiving his PhD. The ceremony was held at Uppsala church and the banquet was in the Uppsala castle.
Early days
I ran into Earl Kirkland at a recent Material Science...

New paper by Israel Fernandez
Congratulations to Israel Fernandez for the publication...

Article in Methods
The article “Continuous Changes in Structure Mapped...