Welcome to Frank Lab
We investigate the mechanism of translation on the ribosome by using cryo-electron microscopy and single-particle reconstruction.
Recent Publications
Article: Structural Bases of Desensitization in AMPA Receptor-Auxiliary
Subunit Complexes
Journal: Neuron
Authors: Edward C. Twomey, et al.
[Abstract]
Article: A Fast and Effective Microfluidic Spraying-Plunging Method for High-Resolution Single-Particle Cryo-EM
Journal: Structure
Authors: Xiangsong Feng, et al.
[Abstract]
Article: Quantitative Characterization of Domain
Motions in Molecular Machines
Journal: The Journal of Physical Chemistry B
Authors: Suvrajit Maji, et al.
[Abstract]
Article: Nmd3 is a structural mimic of eIF5A, and activates
the cpGTPase Lsg1 during 60S ribosome biogenesis
Journal: EMBO
Authors: Andrey Malyutin, et al.
[Abstract]
Article: Advances in the field of single-particle cryo-electron microscopy
over the last decade
Journal: Nature Protocols
Authors: Joachim Frank
[Abstract]
Article: Key Intermediates in Ribosome Recycling Visualized by
Time-Resolved Cryoelectron Microscopy
Journal: Structure
Authors: Ziao Fu, et al.
[Abstract]
Article: Determination of the ribosome structure to a resolution of 2.5 Å
by single-particle cryo-EM
Journal: Protein Science
Authors: Zheng Liu, et al.
[Abstract]
Article: Structure of the STRA6 receptor for retinol uptake
Journal: Science
Authors: Yunting Chen, et al.
[Abstract]
Article: Structure and assembly model for the Trypanosoma cruzi 60S
ribosomal subunit
Journal: PNAS
Authors: Zheng Liu, et al.
[Abstract]
Recent News
Photos of the new Krios Titan microscope
April 25, 2017
Click here for the full Dropbox gallery.
