Welcome to Frank Lab
We investigate the mechanism of translation on the ribosome by using cryo-electron microscopy and single-particle reconstruction.
Recent Publications
Book: Single-Particle Cryo-Electron MicroscopyPublisher: World Scientific
Editor: Joachim Frank
Click here to order.
[Description]
Journal: Nature
Author: Sandip Kaledhonkar, et al.
Journal: Proteomics
Author: Vincent R. Gerbasi, et al.
Article: On the damage done to the structure of the T. acidophilum
proteasome by electron radiation
Journal: Protein Science
Author: Jimin Wang, et al.
[Abstract]
Article: Identification of Changing Ribosome Protein Compositions
using Mass Spectrometry
Journal: Proteomics
Author: Parimal Samir, et al.
[Abstract]
Article: Time-Resolved Cryo-electron Microscopy Using a
Microfluidic Chip
Book: Protein Complex Assembly
Author: Sandip Kaledhonkar, et al.
[Abstract]
Article: Three-Dimensional Analysis of Mitochondrial Crista Ultrastructure
in a Patient with Leigh Syndrome by In Situ Cryoelectron Tomography
Journal: iScience
Author: Stephanie E. Siegmund, et al.
[Summary]
Article: Single-Particle Reconstruction of Biological Molecules:
Story in a Sample (Nobel Lecture)
Journal: Angewandte Chemie
Author: Joachim Frank
[Background]
Book chapter: New Insights into Ribosome Structure and Function
Book: Cold Spring Harbor Perspectives in Biology
Author: Amy Jobe, et al.
[Introduction]
Article: The Jigsaw Puzzle of mRNA Translation Initiation in Eukaryotes:
A Decade of Structures Unraveling the Mechanics of the Process
Journal: Annual Review of Biophysics
Author: Yaser Hashem, et al.
[Abstract]
Recent News
The Indian Statistical Institute in Calcutta
January 24, 2020
Prasanta Chandra Mahalanobis1893 – 1972
I recently was invited by the Indian Statistical Institute in Calcutta to give the convocation address (see http://franxfiction.com/convocation-speech-at-indian-statistical-institute-jan-23-2020/).
I learned the Institute was founded in 1931 by Mahalanobis, whose name rings a bell since I was familiar with the distance measure he introduced.
Wikipedia: “The Mahalanobis distance is a measure of the distance between a point P and a distribution D, introduced by P. C. Mahalanobis in 1936. It is a multi-dimensional...
