May 4, 2018
New Insights into Ribosome Structure and Function
Amy Jobe, Zheng Liu, Cristina Gutierrez-Vargas, and Joachim Frank
In the past 4 years, because of the advent of new cameras, many ribosome structures have been solved by cryoelectron microscopy (cryo-EM) at high, often near-atomic resolution, bringing new mechanistic insights into the processes of translation initiation, peptide elongation, termination, and recycling. Thus, cryo-EM has joined X-ray crystallography as a powerful technique in structural studies of translation. The significance...