April 19, 2018
Identification of ions in experimental electrostatic potential maps.
Jimin Wang, Zheng Liu, Joachim Frank and Peter Moore.
International Union of Crystallography Journal
Cryo-electron microscopy (EM) directly images the distribution of electrostatic potential
within macromolecules, and thus can provide much more information about atomic
charges than X-ray crystallography normally does. The electron scattering length of an
isolated ion is quite different from that of the corresponding neutral atom. The difference
is very large...